Omnivision Image sensors support a serial control interface called SCCB Omnivision SCCB spec
The main difference between SCCB & I2C is that it’s specified as SCLK being output only and active driver instead of open-drain (or tri-state or open-collector). If one actually wants to remove the pull-up on the SCLK and use this feature, it causes a minor issue with some I2C IP blocks in FPGA as they assume open-drain SCLK. Specifically in Xilinx AXI IIC controller, the IP generates 3 signals (scl_i, scl_o, scl_t) which are normally used to control a set of IBUF & OBUFT pads to drive scl_io PAD. The way to use this IP in an SCCB setting is to use the scl_t signal to drive the scl_io. Xilinx OBUFT has an active high tri-state so scl_t is high when scl_io needs to be pulled-up and it’s low with scl_o being also low. So scl_t carries the intent of scl_io signal when active driven. Also scl_i should be connected to scl_t for the IP to sense the driven signal.
One final complication is that if one makes the IIC interface external and uses some of the signals in the Vivado block diagram, Vivado makes all remaining signals external too which creates non-existing pins so all scl_x signals (other than scl_t) should be consumed inside the block diagram. scl_i being connected to scl_t takes care of that signal but scl_o should also be consumed. One can use it as an active low source or “or” it to another signal (it’s always zero so it can’t hurt) for it to be not exported out of the top level wrapper.